Title: Coating of betanin and carvone Co-loaded nanoliposomes with synthesized cationic inulin: A strategy for enhancing the stability and bioavailability
Journal: Food Chemistry
Author: 1.Sajed Amjadi 1.Hadi Almasi 2.Hamed Hamishehkar 1.Mohammad Alizadeh Khaledabad 3.Loong-TakLimc
Year: 2022
Address: 1.Department of Food Science and Technology, Faculty of Agriculture, Urmia University, Urmia 57561-51818, Iran 2.Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 3.Department of Food Science, University of Guelph, Guelph, Ontario N1G2W1, Canada
Abstract: Betanin (BET) and carvone (CAR) as antioxidant and antibacterial compounds were co-loaded in the coated nanoliposomes (NLPs) with cationic inulin to improve their stability and bioavailability. A cationic inulin was successfully synthesized and used for surface coating of the NLPs. The zeta potential, particle size, and PDI values of the coated NLPs were 21.70 ± 7.00 mV, 143.5 ± 15.2 nm, and 0.35 ± 0.03 respectively. The encapsulation efficiency values of the coated NLPs for BE and CAR were 86.1 ± 3.9 and 77.2 ± 5.2 %, respectively. Electron microscopy results showed that the coated NLPs had spherical and core–shell structures. The slowest sustained release profile in the simulated gastrointestinal condition was obtained for the coated NLPs. The physical and oxidative stability of NLPs, as well as the physical stability of loaded compounds were improved by surface coating. In conclusion, the developed nanocarrier is a suitable platform to use all benefits of BET and CAR in the food industry.
Keywords: Surface decoration, Nanoliposome, Physical stability, Oxidative stability, Controlled release, Digestion stability
Application: Antibacterial Properties
Product Model 1: syringe pump(SP102)
Product Model 2:
URL: #https://www.sciencedirect.com/science/article/abs/pii/S0308814621024092#